A giant cell rich form of hemangiopericytomas-solitary fibrous tumors was described by Dei Tos as Giant cell angiofibroma (GCA).
Although originally identified in the orbital region, this tumor may occur in diverse locations.
GCAs are well-circumscribed variably encapsulated, small (median, 3 cm) lesions.
The morphological hallmark is a richly vascularized spindle cell proliferation containing pseudovascular spaces and floret -like multinucleate giant cells.
Mitotic activity range from 1 to 3 mitoses/10 high-power fields.
Treatment of GCA consists of simple tumorectomy.
Source: Pala EE, Beyhan R, Bayol U, Cumurcu S, Kucuk U. Giant Cell Angiofibroma in Unusual Localization: A Case Report. Case Reports in Pathology. 2012;2012:408575. doi:10.1155/2012/408575.