Myxoinflammatory fibroblastic sarcoma is a rare, painless, and intermediate (rarely metastasizing) fibroblastic tumor, which commonly occurs in the extremities, with an equal sex predilection.
This sarcoma is composed of a mixed inflammatory infiltrate along with spindled, epithelioid, and bizarre tumor cells in a background of hyaline and myxoid areas.
In spite of such a distinctive morphology, the tumor can be a diagnostic challenge, simulating inflammatory conditions as well as neoplastic nature.
For accurate diagnosis, the tumor requires extensive clinical, radiological, and pathological investigations.
Kato M, Tanaka T, Ohno T. Myxoinflammatory Fibroblastic Sarcoma: A Radiographical, Pathological, and Immunohistochemical Report of Rare Malignancy. Case Reports in Orthopedics. 2015;2015:620923. doi:10.1155/2015/620923.