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Category: Infographic
What is Rosai Dorfman Disease ? [Pathology Infographic]
Rosai- Dorfman Disease is a rare benign histiocytic disorder in which patients present with painless cervical lymphadenopathy, fever and leukocytosis. The classical findings include emperipolesis and histiocytes staining positive for S100 protein and CD68 and negative for CD1a.
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Cellular Neurothekeoma [Pathology Infographic]
Neurothekeoma is an uncommon, benign, dermal tumour which should not be confused with a Nerve sheath myxoma.
Important features of Cellular Neurothekeoma explained in an infographic .
Raining down appearance of Pigmented Spindle Cell Nevus (Reed Nevus)
Pigmented Spindle Cell Nevus (Reed Nevus) is a distinct pigmented tumour of the skin. Clinically, this lesion presents as symmetrical, sharply circumscribed, darkly pigmented nodule or papule. It is usually noted on the extremities and on the back. This lesion should not be mistaken for a melanoma.
Benign, soft tissue tumour in infants -Fibrous Hamartoma of Infancy [Pathology Infographic]
A 10 month old baby presented with a painless solitary nodule (4 cm in diameter) on the left upper arm.
The lesion was completely excised with clear margins.
Think before you drink – Beware of Holiday Heart Syndrome [Pathology Infographic]
Everyone was in a festive spirit. He was a healthy 50 year old man dancing, drinking and enjoying with his friends. One glass of wine was not enough. He consumed many glasses of alcohol in a short span of time. Suddenly he started sweating, complained of cardiac pain, severe palpitations and respiratory distress. Finally he lost consciousness and collapsed on the floor.
What happened to him ?
Locally Aggressive Adnexal Tumour – Microcystic Adnexal Carcinoma [Pathology Infographic]
A slow growing locally aggressive adnexal tumour presented as a plaque on the cheek of an elderly male.
Just on Hematoxylin and eosin stain search for ductal structures, perineural invasion and deep invasion into the subcutaneous fat.
Immunohistochemistry will finally establish the diagnosis. Pathology of Microcystic Adnexal Carcinoma
[Pathology Infographic] – A cup shaped skin lesion- Warty Dyskeratoma
Warty dyskeratoma is a benign tumour which presents as papule or nodule on the scalp, face, neck and rarely in the oral region.
[Pathology Infographic]- A Slow growing malignant tumour- Aggressive Digital Papillary Adenocarcinoma
Aggressive digital papillary adenocarcinoma is a slow growing, painless malignant sweat gland tumour. It is a rare life-threatening malignant tumour and the diagnosis is easily missed or delayed. Both clinician and pathologist should keep this rare condition in mind when dealing with tumours of the digits.
It is usually located on the fingers. The tumour enlarges over several years. Patients are usually elderly male (50 -70 year old). The clinical presentation is often confusing and can be easily misdiagnosed for a benign lesion such as a ganglion cyst, pyogenic granuloma, or soft-tissue infection.
Microscopic diagnosis is also challenging and it can be wrongly diagnosed as a metastatic papillary adenocarcinoma originating in the colon, thyroid, or breast. Clinicopathological correlation is essential to rule out a possible risk of metastatic carcinoma of the skin.
These are aggressive lesions which can often recur, metastasize to distant sites, and invade local tissues including bone.
Aggressive treatment like amputation of the finger is recommended for this aggressive tumour.
Sudden Cardiac Death – Hypertrophic Cardiomyopathy -Pathology Infographic
He was a 30 year old sportsman with no history of hypertension or heart disease. While playing basketball he suddenly collapsed and died. Autopsy findings revealed that he had Hypertrophic Cardiomyopathy. Diagnosis of this condition is based on gross morphology and microscopic examination of the cardiac tissue.
Microscope - Seeing the Unseen 