Pleomorphic hyalinizing angiectatic tumors (PHATs) are non-metastasizing soft-tissue tumors of uncertain lineage occurring within the superficial subcutaneous tissues and muscles .
Presents in adults between the ages of 10 and 83 years (median age of 51 years), PHATs are more commonly observed in females than in males.
The majority of affected patients present with slowly-growing, painless masses, most commonly involving the lower extremities.
Rarer tumor sites include the arm, chest wall, axilla, popliteal fossa, buttocks, inguinal region, perineum, buccal mucosa and breast.
SUZUKI K, YASUDA T, HORI T, et al. Pleomorphic hyalinizing angiectatic tumor arising in the thigh: A case report. Oncology Letters. 2014;7(4):1249-1252. doi:10.3892/ol.2014.1883.
Is your hairdresser coughing, sniffing and has a chronic respiratory problem? Are you concerned about her health? She should consult a doctor immediately.
According to a study by Ümran Toru et al smoking may aggravate occupational airway disease in hairdressers. Smoking increase both respiratory complaints and decreased respiratory functions in this profession.
In a study by Brisman et al. that was performed with the aim of evaluating the wheezing, dry cough, and nasal congestion in hairdressers, the survey on respiratory symptoms, atopy, smoking, and job history was answered by three thousand nine hundred and fifty-seven female hairdressers and four thousand nine hundred and five reference women from general population. When compared with references, the ratios of all three symptoms in hairdressers were found to be high and hairdressing was correlated with an increased incidence of respiratory symptoms. The combined effect of hairdressing and smoking was found to be lower than expected and it was proposed that smoking has negative modifying effect.
In a study by Slater et al., the occupational respiratory symptoms in hairdressers were examined. A survey was done on a hundred hairdressers and employees of one hundred and six offices and stores covering their respiratory symptoms, demographic data and smoking habits. Respiratory functions were measured before each shift. Asthma symptoms, diagnosis, and asthma attack prevalence of hairdressers in the previous twelve-month period were found to be high. High symptom prevalence in hairdressers was associated with high smoking ratios and average pulmonary function values were found to be low.
According to the study cough, phlegm, and chest tightness were noted more in smokers compared to nonsmokers. Rhinitis was also more in smoking hairdressers.
“In conclusion, hairdressers were determined as an occupational group the majority of which was formed by women, in which respiratory complaints and rhinitis history were frequently observed in the subgroup in which cotinine was above 500 ng/mL and where both occupational and smoking status had an additive effect.”
Cutting off smoking could help in this profession.
- Ümran Toru, Peri Meram Arbak, Kezban Özmen Süner, Özlem Yavuz, and Naciye Karataş, “Relationship between Respiratory Tract Complaints, Functional Status, and Smoking in Hairdressers, Auto Painters, and Carpenters,” The Scientific World Journal, vol. 2014, Article ID 802705, 7 pages, 2014. doi:10.1155/2014/802705
- “The incidence of respiratory symptoms in female Swedish hairdressers,” The American Journal of Industrial Medicine, vol. 44, no. 6, pp. 673–678, 2003.
- “Occupational respiratory symptoms in New Zealand hairdressers,” Occupational Medicine, vol. 50, no. 8, pp. 586–590, 2000.
“What the mind does not know, the eyes do not see”.
Epithelioid Sarcoma is a rare malignat tumour and can look deceptively benign.
It was first described by Laskowski in 1961 as “sarcoma aponeuroticum” as it involved aponeuroses and surrounding structures.
Later Enzinger introduced the current term “epithelioid sarcoma”.
Only an expert histopathologist with many years experience can think of this rare tumour on haematoxylin and eosin stain.
Smart pathologists have an eye to catch the clues immediately. Later, immunohistochemistry and cytogenetics help in confirming the diagnosis.
This tumour can be mistaken for chronic inflammatory condition, necrotizing granulomas, and various fibrohistiocytic tumours.
Wrong diagnosis can delay proper treatment and can actually kill a young patient.
There are star pathologists in every part of the world. I dedicate every blog post for those excellent, silent workers.