Nerve sheath myxoma [Pathology Infographic]

Nerve sheath myxoma is a rare myxoid tumour of probable nerve sheath origin. It is characterized by low cellularity and large amounts of myxoid matrix. 

The strong positivity of tumor cells for S-100 protein, which is a well-established marker for Schwann cells and myelin sheath, favors the Schwann cell origin.

 

Benign, soft tissue tumour in infants -Fibrous Hamartoma of Infancy [Pathology Infographic]

A 10 month old baby presented with a painless solitary nodule (4 cm in diameter) on the left upper arm.

The lesion was completely excised with clear margins.

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Locally Aggressive Adnexal Tumour – Microcystic Adnexal Carcinoma [Pathology Infographic]

A slow growing locally aggressive adnexal tumour  presented as a plaque on the cheek of an elderly male.

 Just on Hematoxylin and eosin stain search for ductal structures, perineural invasion and deep invasion into the subcutaneous fat.

Immunohistochemistry will finally establish the diagnosis. Pathology of Microcystic Adnexal Carcinoma

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