Coccidioidomycosis was first described in 1892 by Alejandro Posadas (a medical student from Argentina), when he evaluated Domingo Ezcurra, a soldier who presented with a verrucous papule on the right cheek. A diagnosis of mycosis fungoides with psorospermia was considered. After having observed spherical organisms with a double-refractile outer wall, that appeared similar to the protozoan Coccidia, Posadas and his mentor, Robert Wernicke, believed that these organisms had a parasitic origin. Ezcurra died in 1898 despite many topical treatments. His head is now conserved in a museum in Buenos Aires.
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