Raining down appearance of Pigmented Spindle Cell Nevus (Reed Nevus)

Pigmented Spindle Cell Nevus (Reed Nevus) is a distinct pigmented tumour of the skin.  Clinically, this lesion presents as symmetrical, sharply circumscribed, darkly pigmented nodule or papule.  It is usually noted on the extremities and on the back. This lesion should not be mistaken for a melanoma.

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Benign, soft tissue tumour in infants -Fibrous Hamartoma of Infancy [Pathology Infographic]

A 10 month old baby presented with a painless solitary nodule (4 cm in diameter) on the left upper arm.

The lesion was completely excised with clear margins.

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Locally Aggressive Adnexal Tumour – Microcystic Adnexal Carcinoma [Pathology Infographic]

A slow growing locally aggressive adnexal tumour  presented as a plaque on the cheek of an elderly male.

 Just on Hematoxylin and eosin stain search for ductal structures, perineural invasion and deep invasion into the subcutaneous fat.

Immunohistochemistry will finally establish the diagnosis. Pathology of Microcystic Adnexal Carcinoma

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Tadpole shaped ducts in Syringoma -Pathology Infographic

 

Syringoma is a benign tumour derived from acrosyringium, the intraepidermal portion of eccrine/apocrine sweat ducts.

They are largely asymptomatic tumours and are predominantly of cosmetic significance.

Syringomas are typically localized to the eyelids of middle-aged women; however, other sites include the ventral surface of the trunk, forehead, neck, axillae, abdomen and rarely the penis, vulva, buttocks, moustache area and scalp .

A classification scheme has been proposed by Friedman and Butler  identifying 4 variants of syringoma: a localized form, a form associated with Down syndrome, a familial form and a generalized form (encompassing multiple and eruptive syringomas). Incidental Syringomas of the Scalp in a Patient with Scarring Alopecia. Case Rep Dermatol. 2015 Jul 24;7(2):171-7.

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